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At the same time, Caspase-1 processes Gasdermin D (GSDMD), thereby allowing the N-terminal GSDMD domain to form pores in the plasma membrane, which contribute to the egress of IL-1 and also cause the lytic form of cell death known as pyroptosis 10,11,12,13

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Szlcyxzx202109), the Suzhou Key Laboratory (SZS2024016), the Suzhou Multicenter Clinical Research Project on Major Diseases (no

[DOI] [PMC free article] [PubMed] [Google Scholar] [61].Chetchotisakd P, Chierakul W, Chaowagul W, et al